Research activities

Research and development of a decontamination process utilizing vapor phase hydrogen peroxide

CV

Since 2011: ICT Prague, Organic Technology PhD program
2009 - 2011: ICT Prague, Drug Production master degree program
Thesis title: Potentiation study of chemical contaminants degradation in hydrogen peroxide decontamination
Since 2008: Member of the research team at the Department of Organic Technology, ICT Prague
2006 - 2009: ICT Prague, Drug Production and Synthesis bachelor degree program
Thesis title: Molecular structure effects in degradation by vapor-phase hydrogen peroxide in combination with UV radiation (UV/VPHP process)

Prizes

2010: 1st place at Student Scientific Conference – ICT Prague, Czech Republic

Conferences

2010: Student scientific conference (talk) – ICT Prague, Czech Republic
2008: Student scientific conference (talk) – ICT Prague, Czech Republic

Current research project

VPHP process (Vapor Phase Hydrogen Peroxide) is a modern decontamination method utilizing vapor phase hydrogen peroxide as the effective agent. So far, it has been used for bio-decontamination such as US postal service buildings remediation after anthrax terrorist attacks in 2001, medical tools or areas sterilization or in food industry. Intensive research is now being pursued aiming for its possible use for degradation of environmental polluting chemical contaminants (pesticides, industrial poisons, …), war chemicals and especially biological active compounds like medicaments, hormones etc. Vapor phase hydrogen peroxide fulfills the idea of an ideal decontamination agent in many ways. Ease of use, non-toxicity, low cost, safety, no odor and applicability in large areas or whole buildings are its main advantages. On the other hand, low efficiency on some groups of chemicals and incompatibility with some materials (paper, specific plastics, metals) are its disadvantages. For that reason, one of the research areas is also focused on studying the compatibility of materials with VPHP and possibilities of vapor phase hydrogen peroxide effects potentiation by elevating the ratio of the formed vs. to H2O2. This can be achieved by VPHP combining with a chemical agent like organic bases (mostly tertiary amines), a physical agent like UV light, physico-chemical systems like photocatalysis with TiO2 nano-particles and UV light, or combination of all mentioned above. At present, the research is focused on VPHP method efficiency testing on wide range of biological active compounds, for example platinum-based cytostatics. Studies of the degradation and potentiation process mechanisms, development of advanced analytical methods (GC/MS, HPLC/MS) for the identification of the degradation products, and also new ways of fast reaching of high concentrations of VPHP in the air are now in progress.